E-ISSN 2231-3206 | ISSN 2320-4672
 

Original Research

Online Publishing Date:
28 / 06 / 2016

 


Serum magnesium levels in type 2 diabetes with metabolic syndrome

K. C. Razeena, Jean Maliekkal, Geetha Nair.


Abstract
Background: Diabetes is a serious illness with multiple complications and premature mortality. Type 2 diabetes is the predominant form of diabetes worldwide, and it accounts for 90% of cases globally. Large majority with Type 2 diabetes have the metabolic syndrome (MS). MS is a widely prevalent disorder, and it is associated with increased risk for the development of cardiovascular disease, cerebrovascular disease, and renal disease.

Aims and Objectives: The present study was conducted to find out the relationship between serum magnesium levels and MS.

Materials and Methods: The study was conducted in 135 diabetic patients. They were divided into 2 groups. 90 Type 2 diabetic patients with MS and 45 Type 2 diabetic patients without MS. 45 normal healthy adults were included in the control group.

Results: The study showed that mean serum magnesium levels were significantly lower in patients with MS when compared with that of healthy adults. Correlation analysis revealed a significant negative correlation between serum magnesium levels and fasting blood sugar, systolic blood pressure (BP), diastolic BP, triglyceride levels, and a positive correlation between serum magnesium and high-density lipoprotein levels.

Conclusion: MS is highly prevalent in our population. Low serum magnesium levels play an important role in the pathogenesis of MS. Studies have shown that magnesium intake is inversely associated with incident MS and its components. Hence, magnesium supplementation in young adults can prevent the development of MS and thereby the complications related to it.

Key words: Magnesium; Metabolic Syndrome; Type 2 Diabetes


 
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How to Cite this Article
Pubmed Style

K. C. Razeena, Jean Maliekkal, Geetha Nair. Serum magnesium levels in type 2 diabetes with metabolic syndrome. Natl J Physiol Pharm Pharmacol. 2016; 6(6): 520-525. doi:10.5455/njppp.2016.6.0615307062016


Web Style

K. C. Razeena, Jean Maliekkal, Geetha Nair. Serum magnesium levels in type 2 diabetes with metabolic syndrome. https://www.njppp.com/?mno=231710 [Access: March 14, 2024]. doi:10.5455/njppp.2016.6.0615307062016


AMA (American Medical Association) Style

K. C. Razeena, Jean Maliekkal, Geetha Nair. Serum magnesium levels in type 2 diabetes with metabolic syndrome. Natl J Physiol Pharm Pharmacol. 2016; 6(6): 520-525. doi:10.5455/njppp.2016.6.0615307062016



Vancouver/ICMJE Style

K. C. Razeena, Jean Maliekkal, Geetha Nair. Serum magnesium levels in type 2 diabetes with metabolic syndrome. Natl J Physiol Pharm Pharmacol. (2016), [cited March 14, 2024]; 6(6): 520-525. doi:10.5455/njppp.2016.6.0615307062016



Harvard Style

K. C. Razeena, Jean Maliekkal, Geetha Nair (2016) Serum magnesium levels in type 2 diabetes with metabolic syndrome. Natl J Physiol Pharm Pharmacol, 6 (6), 520-525. doi:10.5455/njppp.2016.6.0615307062016



Turabian Style

K. C. Razeena, Jean Maliekkal, Geetha Nair. 2016. Serum magnesium levels in type 2 diabetes with metabolic syndrome. National Journal of Physiology, Pharmacy and Pharmacology, 6 (6), 520-525. doi:10.5455/njppp.2016.6.0615307062016



Chicago Style

K. C. Razeena, Jean Maliekkal, Geetha Nair. "Serum magnesium levels in type 2 diabetes with metabolic syndrome." National Journal of Physiology, Pharmacy and Pharmacology 6 (2016), 520-525. doi:10.5455/njppp.2016.6.0615307062016



MLA (The Modern Language Association) Style

K. C. Razeena, Jean Maliekkal, Geetha Nair. "Serum magnesium levels in type 2 diabetes with metabolic syndrome." National Journal of Physiology, Pharmacy and Pharmacology 6.6 (2016), 520-525. Print. doi:10.5455/njppp.2016.6.0615307062016



APA (American Psychological Association) Style

K. C. Razeena, Jean Maliekkal, Geetha Nair (2016) Serum magnesium levels in type 2 diabetes with metabolic syndrome. National Journal of Physiology, Pharmacy and Pharmacology, 6 (6), 520-525. doi:10.5455/njppp.2016.6.0615307062016